Molecular and Cellular Mechanisms of Allergic Diseases

Each immune component has its own mechanism pathways for production and function. Molecular and cellular factors involved in these mechanisms must also be studied to get an insight on the immune system and discover solutions for any immune disorders. Molecular and cellular mechanisms which mediate allergic inflammation involve several multiple mediators, cell type and lymphocytes/ interleukins pathways. Allergy or allergic diseases is caused due to hypersensitivity of immune system in response to the genetics or environmental factors. The allergy is of different types with difference mechanism for each. The symptoms range from Rhinitis, inflammation, Allergic urticaria, Atopic eczema, Conjunctivitis, Angioedema and Anaphylaxis. The cure for several involves therapies, vaccines, Antihistamines, Decongestants, Moisturizing creams (emollients) and Steroid medication.

Allergic diseases include anaphylaxis, food allergies, forms of asthma, conjunctivitis, eczema, eosinophilic disorders, and drug & insect allergies. According to the International Study of Asthma and Allergies in Childhood (ISAAC), an estimated hay fever prevalence in 13 to 14 year old children was approximately 22.1% globally, with 29.5% in Africa, 23.9% in Asia, 15.8% in the Indian subcontinent, 23.7% in Latin America, 33.3% in North America, 12.3% in Northern & Eastern Europe, 39.8% in the Oceania, and 21.2% in the Western Europe. It is essential for patients to receive an accurate diagnosis of hay fever. In addition, food allergies are on the rise. An estimated 17 million Europeans have food allergies. Furthermore, the latest diagnostic strategies for allergies and research on new approaches for treatment are expected to drive the market.